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Figure 1
The separation of acetaminophen and codeine phosphate on a Pinnacle II ™ C18
column shows symmetrical peak shape.
With the design of Pinnacle II ™ columns, Restek
achieves complete control over the HPLC column
manufacturing chain. We can go a step further than
most to ensure consistent quality and reproducibility
because we manufacture the silica, perform the sta-
tionary phase bonding and column packing in-
house, and apply our stringent quality testing
throughout the whole process. The ability to consis-
tently manufacture silica at a specified pore volume,
surface area, pore size distribution, and particle size
is part of the equation in providing columns that
achieve reproducible analyses.
Pharmaceutical Applications
Notice how a Pinnacle II™ C18 column provides
good peak shape for acetaminophen and codeine
phosphate (Figure 1). You'll get this level of quality
in your results, from analysis to analysis.
Innovators of High Resolution Chromatography Products
the
in this issue
Super-Clean™ Gas Filters
…pg. 6
New Reference Texts
…pg. 7
Restek On-the-Road Seminars
…pg. 7
SilcoCan ™ Canisters for Low-Level
Sulfur Analysis & Storage
…pg. 8
Improved Passive Air Sampling Kits
…pg. 9
Rtx®-5 Amine GC Column for
Trace-Level Pharmaceutical Analyses
…pg. 10-11
ChromaGas Hydrogen and
Nitrogen LC/MS Generators
…pg. 11
Trace Explosives Analysis
…pg. 12
Rt-QPLOT™ GC Column Boasts
Improved Deactivation
…pg. 13
Peak Performers
…pg. 14-15
Behind the Scenes
…pg. 16
Summer’01
by Greg France, HPLC Product Marketing Manager
INTERNATIONAL
Pinnacle II™
A New Line of HPLC Columns from Restek
Advantage
Pinnacle II™
HPLC Columns
…pg. 1–3
FAPAS® Food Quality
Testing Reference
Materials
…pg. 4
ISO/DIS Water Quality
Testing Reference
Materials
…pg. 5
Pinnacle II™ columns are manufactured using
Restek silica, which features a controlled particle
size distribution and spherical shape. It is available
in 5µm particle size, with a pore diameter centered
at 110Å, and a sur-
face area of
~180m2/g. These sili-
ca particles address
the growing demand
for narrower
columns and faster
flow rates in an
attempt to decrease
analyses times. The
phases offer similar
selectivity to the orig-
inal line of Pinnacle ™
columns.
✔ Featuring Restek silica—manufactured, bonded, and QA tested in-house.
✔ Wide range of applications: environmental, pharmaceutical,
nutraceutical, foods, flavors, and fragrances.
✔ Currently available with C18, C8, phenyl, and cyano stationary phases.
new
1
Peak List Conc.
1. acetaminophen 1200µg/mL
2. codeine phosphate 246µg/mL
Sample:
Inj.: 1.0µL
Solvent: mobile phase
Column: Pinnacle II™ C18
Catalog #: 9214565
Dimensions: 150x4.6mm
Particle size: 5µm
Pore size: 110Å
Conditions:
Mobile phase: 10mM potassium phosphate
monobasic with 0.1% v/v TEA,
pH 3.0:acetonitrile (90:10)
Flow: 1.0mL/min.
Temp.: 27°C
Det.: UV @ 210nm
2
3 3.5 4 4.5
LC_0152