TUBING
79
FlexiblePeristaltic Tubing
IsmapreneTubing (PharMed
®
)
XX
Excellent chemical resistance
for traditional peristaltic
pump tubing
XX
Offers FDA andUSPClass VI
certification
PharMed Ismaprene tubing has
longbeen the tubingof choice
formanydemandingapplications
whereotherpolymerblendshave
beenunsuitable for use.
With strong chemical resistance, excellent lifetime, and low gas
permeability— coupled with industry-standard certifications—
PharMed tubing is offered in options for standard pumps as well
as for pumps requiring 2-stop and 3-stop tubing. Special versions
are available with welded stops for applications where repeated
autoclavingmust takeplace.
Special Properties
The ideal tubing forpharmaceutical andmedical applications,
and for foodstuffs
Advantages
•Recommended for cell culturesand tissue
• Ideal forproductionfiltration, fermentation,
andbioreactorprocess lines
•Very long service-life
•Non-toxicandnon-hemolytic
• Impermeable tonormal light andUV-radiation
•Appropriate formedical productsand foodstuffs
•Lowparticulate spallation
•Canbeautoclaved repeatedly
•Withstands repeatedCIPandSIPcleaningand sterilization
•MeetsUSPClassVI, FDA, andNSFcriteria
Limitations
•Potential leachingof additives (lubricants)
Physical Properties
•Thermoplasticelastomerbasedonpolypropylene
•Firm, opaque, beigecolor
ServiceTemperature
Range
-60 °C to+135 °C (-75 °F to+275 °F)
Applications
Acids Good
Alkaline solutions Good
Solvents Not recommended
Pressure Not recommended
Vacuum Excellent
Viscousmedia Good
Sterilemedia Excellent
Complieswith the
FollowingStandards
FDA21CFRPart 177.2600;USPharmacopoeaClassVI,
NSF listed (Standard51)
Sterilization
Autoclavablewith steam, 30minutesat 1bar (15psi) and
141 °C (250 °F)Gas sterilizationwithEthyleneoxide.
Sterilizationwith radiationup to2.5mrad.
Caution:Use special tubingversion (welded stoppers)
whenautoclaving2or 3-stop color-coded tubing.
Permeability
Volumeofgas [cm3] xwall thickness [mm]
Areaof tubing ID [cm2] x time [sec]
xpressuredropacross tubingwall [cmHg]
x10
-10
CO
2
1200
O
2
200
N
2
80
Odor and taste
Low
Toxicity
Non-toxicandnon-hemolytic
Tubing
life
at 0bar 1000+hrs
at 0.7bar 1000hrs
SPECIFICATIONS&DETAILS
Tygon
®
3350SITubing
XX
Platinum-cured silicone tubing
XX
Featuresultra-smooth inner-bore
XX
Biocompatible for life
science applications
Tygon 3350 SI tubing is a special
silicone-based tubing that
undergoesaspecialtreatmentwith
platinum toensurea very smooth
internal surface. This surface
featurehelps improve thematerial’s usewithbiological applications
wheresolidmaterialmaybepresent.Additionally,thematerialexhibitsa
low-levelofprotein-bindingaswellasbeingnon-toxic,helpingtomake
thismaterial the topchoice formany life scienceapplications.
Special Properties
Theplatinum-cured silicone tubingwithanultra-smooth
inner surface for sanitary transferof sensitivefluids
Advantages
•Steamautoclavability
•Excellentbiological compatibility
•Ultra-smooth inner-bore reducespotential forparticleentrapment
•Lower level ofproteinbinding
•Entirelynon-toxic, non-hemolytic, andnon-pyrogenic
•Weather, ozone, sunlight, and radiation resistant
•Resistant to fungus
•Odorless
Limitations
•Not suitable for concentrated solvents, oils, acids, or
diluted sodiumhydroxide
•Relativelyhighgaspermeability
Physical Properties
•Thermal set rubber
•Siloxanepolymersandamorphous silica
•Soft, translucent, clear to light amber
•Excellent compression strength
ServiceTemperature
Range
-60 °C to+200 °C (-75 °F to+392 °F)
Applications
Acids Limited
Alkaline solutions Limited
Solvents Limited
Pressure Not recommended
Vacuum Good
Viscousmedia Fair
Sterilemedia Excellent
Complieswith the
FollowingStandards
USPharmacopoeaXXIIICl.Vl, FDA21CFR, Part 177.2600.
Alsoexceeds3A sanitary standards.
Sterilization
Autoclavablewith steam, 30minutesat 1bar (15psi) and
121 °C (250 °F)Gas sterilizationwithEthyleneoxide
Sterilizationwith radiationup to2.5mrad.
Permeability
Volumeofgas [cm3] xwall thickness [mm]
Areaof tubing ID [cm2] x time [sec]
xpressuredropacross tubingwall [cmHg]
x10
-10
CO
2
25147
O
2
4715
N
2
2284
Odor and taste
None
Toxicity
Non-toxic
Tubing
life
at 0bar 200hrs
at 0.7bar 100hrs
SPECIFICATIONS&DETAILS
