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Welcome to the new look for your Restek Advantage!
When we sat down to plan this issue, one of our goals was to share more chromatography
news and better connect with you, our reader. That’s how our new Hot Topics and Restek
Connections departments came to be.
Of course, as always, much of this Advantage highlights the application work of our
Innovations Lab, where we’re lucky to have seasoned veterans working alongside young,
enthusiastic chemists to solve your toughest problems. Rick Lake and Ty Kahler show you
how to get the most selectivity for your LC separations. Their work employs the hydropho-
bic subtraction model to define a highly selective and orthogonal set of 4 USLC™ columns.
You will also be interested in reading our article on marijuana potency testing, PLOT
columns in process GC, wool in GC inlet liners, large volume splitless injection... We have
something inside for every analyst.
Finally, we also set up a new email address: Use it to let us know
what you think of your new Restek Advantage. I say “ your” because we create this techni-
cal document with your needs and interests in mind. Your feedback will be invaluable for
assembling future issues.
Cheers!
Jack Cochran
Director of New Business & Technology
In This Issue
Restek Connections. . . . . . . . . 2
Hot Topics. . . . . . . . . . . . . 3
Technical Articles . . . . . . . . 4–15
Marijuana Potency Testing by LC or GC. . . 4–5
Simplify HPLC and UHPLC Method
Development. . . . . . . . . . . . . . . 6–7
Large Volume Splitless Injection with an
Unmodified GC Inlet. . . . . . . . . . . 8–9
Extending PLOT Column Technology to
Process GC Analyzers. . . . . . . . . .10–11
Rethinking the Use of Wool With
Splitless GC . . . . . . . . . . . . . . 12–13
Innovators in Chromatography
(Guest Editorial: Dr. Chris Marvin):
Brominated Flame Retardants
by LC-MS. . . . . . . . . . . . . . . .14–15
About Restek Corporation
A leading innovator of chromatography solutions
for both LC and GC, Restek has been developing
and manufacturing columns, reference standards,
sample preparation materials, accessories, and
more since 1985. We provide analysts around the
world with products and services to monitor the
quality of air, water, soil, food, pharmaceuticals,
chemicals, and petroleum products. Our experts
enjoy diverse areas of specialization in chemistry,
chromatography, engineering, and related fields
as well as close relationships with government
agencies, international regulators, academia, and
instrument manufacturers.
Patents and Trademarks
Restek patents and trademarks are the property
of Restek Corporation. Other trademarks appear-
ing in Restek literature or on its website are the
property of their respective owners. The Restek
registered trademarks used here are registered in
the United States and may also be registered in
other countries.
You Have Opinions... AndWe Want Them.
We chemists are an opinionated bunch, so the odds are good that you have
some thoughts about the Restek Advantage. Love it? Hate it? Want to see
something different in the next issue? Maybe you have a response to one of our
technical articles? Whatever you have to say, let’s hear it! Email your comments to
and you may even see them in an upcoming issue.
Letter from the Bench
| Feedback? E-mail 2
Restek Connections