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Figure 2 Fast, selective analysis of benzodiazepines is made possible by combining the speed of UHPLC with the
enhanced selectivity of the 1.9μm Pinnacle™ DB PFP Propyl column.
• 7 •
2007 vol. 3
Pharmaceutical
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Peak List: Conc (µg/ml)
1. 7-amino clonazepam* 20
2. 7-amino flunitrazepam* 20
3. bromazepam 100
4. oxazepam 100
5. lorazepam 100
6. clonazepam 100
7. nitrazepam 100
8. nordiazepam 100
9. flunitrazepam 100
10. diazepam 100
* metabolite
Sample:
Inj.: 1µL
Conc.: as listed
Sample diluent: starting mobile phase (80:20 A:B)
Column: A. C18 Column
B. 1.9µm Pinnacle™ DB PFP Propyl
Cat. #: A. 9414212
B. 9419212
Dimensions: 100mm x 2.1mm
Particle size: 1.9µm
Pore size: 140Å
Instrument: Jasco X-LC
Conditions:
Mobile phase: A: 0.1% formic acid in water
B: 0.1% formic acid in acetonitrile
Time (min.) %B
0 20
1 20
6 80
Flow: 0.6 mL/min.
Temp.: 40°C
Det.: UV @254 nm
LC_PH0451
Compounds
coelute on a
C18 column
A) C18 Column B) 1.9μm Pinnacle™ DB PFP Propyl
1.9μm Pinnacle™ DB HPLC Columns
Physical Characteristics:
1.9µm Pinnacle™ DB C18 column, 2.1mm cat. # price
30mm 9414232 $440
50mm 9414252 $460
100mm 9414212 $520
1.9µm Pinnacle™ DB Silica column, 2.1mm cat. # price
30mm 9410232 $440
50mm 9410252 $460
100mm 9410212 $520
1.9µm Pinnacle™ DB PFP Propyl column, 2.1mm cat. # price
30mm 9419232 $440
50mm 9419252 $460
100mm 9419212 $520
1.9µm Pinnacle™ DB Biphenyl column, 2.1mm cat. # price
30mm 9409232 $440
50mm 9409252 $460
100mm 9409212 $520
1.9µm Pinnacle™ Aqueous C18 column, 2.1mm cat. # price
30mm 9418232 $440
50mm 9418252 $460
100mm 9418212 $520
particle size: 1.9µm
pore size: 140Å
endcap: yes
pH range: 2.5 - 7.5
temperature limit: 80°C
More phases coming soon!