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800-356-1688
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FamotidineonUltra II™Aromax
Sample:
Inj.:
10µL
Conc.:
100µg/mL famotidine, 10µg/mL each impurity
Sample diluent: methanol
Column:
Ultra II™Aromax
Cat.#:
9607565
Dimensions:
150mm x 4.6mm
Particle size:
5µm
Pore size:
100Å
Conditions:
Instrument:
Shimadzu ProminenceUFLC
XR
Mobile phase:
20mM potassium phosphate (pH 2.5):methanol
Time (min.)
%B
0
5
15
35
Flow:
2.0mL/min.
Temp.:
40°C
Pressure:
140bar
Det.:
UV@ 268nm
Peak List
Ret.Time (min.)
1. impurity A
3.779
2. famotidine
8.264
3. impurity D
9.180
4. impurity C
9.911
5. impurity B
14.018
LC_PH0495
Peak List
Ret.Time (min.)
1. impurity A
2.094
2. famotidine
4.460
3. impurity D
4.937
4. impurity C
5.334
5. impurity B
7.480
Sample:
Inj.:
5µL
Conc.:
100µg/mL famotidine, 10µg/mL each impurity
Sample diluent: methanol
Column:
Ultra II™Aromax
Cat.#:
9607313
Dimensions:
100mm x 3.2mm
Particle size:
3µm
Pore size:
100Å
Conditions:
Instrument:
Shimadzu ProminenceUFLC
XR
Mobile phase:
20mM potassium phosphate (pH 2.5):methanol
Time (min.)
%B
0
5
8
35
Flow:
1.2mL/min.
Temp.:
40°C
Pressure:
345bar
Det.:
UV@ 268nm
LC_PH0494
Peak List
Ret.Time (min.)
1. impurity A
0.892
2. famotidine
2.082
3. impurity D
2.292
4. impurity C
2.517
5. impurity B
3.540
LC_PH0493
Sample:
Inj.:
2µL
Conc.:
100µg/mL famotidine, 10µg/mL each impurity
Sample diluent: methanol
Column:
Ultra II™Aromax
Cat.#:
9607853
Dimensions:
50mm x 3.0mm
Particle size:
2.2µm
Pore size:
100Å
Conditions:
Instrument:
Shimadzu ProminenceUFLC
XR
Mobile phase:
20mM potassium phosphate (pH 2.5):methanol
Time (min.)
%B
0
5
4
35
Flow:
1.2mL/min.
Temp.:
40°C
Pressure:
480bar
Det.:
UV@ 268nm
Fastest!
2.2μm
Faster!
3μm
Fast!
5μm
8min.
15min.
4min.
