691
GCCHROMATOGRAMS |
PHARMACEUTICAL
Basic Drugs, Anesthetics
1. amitriptyline
2. trimipramine
3. imipramine
4. nortriptyline
5. doxepin
6. desipramine
7. maprotyline
8. clomipramine
1
2
3
4
5
6
7
8
min.
1
2
3
4
5
6
Antidepressants (BasicDrugs) (Underivatized)
Rtx®-1701
Column:
Rtx
®
-1701, 15m, 0.25mm ID, 0.25µm (cat.# 12020)
Sample:
1.0µL split injection of antidepressants
Conc.:
25ng/component
Oven temp.:
225°C
Inj./det. temp.:
250°C/260°C
Carrier gas:
helium
Linear velocity:
30cm/sec. set@ 225°C
FID sensitivity:
2.56 x 10
-10
AFS
Split ratio:
40:1
GC_PH00264
UnderivatizedAntihistamines (BasicDrugs)
Rtx®-5Amine
1. phenylpropanolamine
2. ephedrine
3. pseudoephedrine
4. pheniramine
5. diphenhydramine
6. doxylamine
7. phenyltoloxamine
8. methapyrilene
9. chlorpheniramine
10. brompheniramine
11. triprolidine
Column:
Rtx
®
-5 Amine, 30m, 0.32mm ID, 1.0µm
(cat.# 12354)
Sample:
1.0µL split injection of antihistamines
Conc.:
1,000ng/µL
Oven temp.:
130°C (hold 5min.) to 305°C
@ 10°C/min. (hold 5min.)
Inj./det. temp.:
305°C
Carrier gas:
hydrogen
Linear velocity:
43cm/sec. set@ 130°C
FID sensitivity:
6.4 x 10
-11
AFS
Split ratio:
50:1
GC_PH00247
min.
5
10
15
20
25
1
2
11
10
9
8
7
6
5
4
3
LocalAnesthetics
Rxi®-5ms
GC_PH00860
Column:
Rxi
®
-5ms, 30m, 0.53mm ID, 1.00µm (cat.# 13455)
Sample:
50µg/mL each component inmethanol
Inj.:
1.0µL split (10:1), 4mm split inlet liner withwool (cat.# 20781)
Inj. temp.:
250°C
Carrier gas:
helium, constant flow
Flow rate:
5.0mL/min.
Oven temp.:
200°C (hold 4min.) to 320°C@ 30°C/min. (hold 3min.)
Det.:
FID@ 300°C
1. benzocaine
2. prilocaine
3. lidocaine
4. procaine
5. tetracaine
6. bupivacaine
7. dibucaine
Goodpeak shape for
underivatizedbasicdrugs.
Rxi®Technology!
Exceptionally inert,
ultra low- bleed
capillary columns.
Website :
E-mail :
TelNo : 03 9762 2034 . . . inAUSTRALIA
Mar 2011
