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GC Column Mix for Pharma Method Development
Rxi-5Sil MS
Phase:
Non-polar
Polar
Thermal Stability: High (360)
350
320
Low (260)
Inst. Compat.
GC/MS
GC/FID only
Deactivation: Balanced
Amine (follow with same deactivation for liners)
DA vs DB option
Rxi-17Sil MS
Rxi-624Sil MS
Stabilwax
Four GC column phases recommended for organic volatile impurities
•Wide variation in selectivity
•Highly thermally stable columns
•Very inert
•Reproducible from column to column
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