ContinuousApplication: 8Stream
micro-ScaleBioreactor System
Continuousmonitoring is required
Productionmonitoring for a specialty chemical
Nutrient monitoring& feed rate formicrobes
Oxygenmonitoring& feed rate formicrobes
Fermentor off gas analysis is required
Sampling thebroth is complicated
Themicrobeswill plug virtually any automatic
samplingmechanism
(they continue togrow… things shut)
Theoff gas concentration indicates production yield
Therearemultiple small systems
In this case thereare 8 reactors
(90 secondcycles)
Process flow rates are small <1 liter/minute
Calibration for the semivolatile organic is problematic
Manual sampling&monitoring is virtually impossible
