new 2012+ extended to 4 metres MAX per module but 8 metres 2 modules in series
column resistive heating 6 foot long MAX ) . . . compromised “intrinsic” column efficiency 0.28mm ID Columns ~3000 plates/meter Total N(t) 6000 compared to high resolution 0.28mm ID 30m N)t) 90,000 BUT analyses in 2 minutes vs 20-30 minutes optimised
““old” GCs : large Lab GC Ovens
High Enengy;kilowatts; slow heating 60degC/min. . . at lower temp ranges 0-100C; 40 100-200; 200-300 30 300-400 ??? Cool Down 5minutes to 50C, 10mins to 40C
“new” Calidus FAST GC
300 Watts max; 300degC permin . . . ideal for portable applications ambient +5 degC to 400 degC Cool down < 2mins to 40 degC
“FAST” GC some “more practical” Issues ”Theory”/Data HTM Calidus GC 2012 PDF Overview
this is still but an Overview of Calidus FastGC for more details you will need to consult with Us !
Fast GC vs idealised but slower R&D type separations
HC to C20 Details Restek E1387 Mix
Higher resolution > L and much greater time required
If you don’t need the Resolution then you can save time - Accuracy improved . . . 10-20scans per peak
accuracy depends on speed of the A/D / time slicing of the Data Sys across peaks - obvious compromise in idealised Restek chromatogram - also may suffers in accuracy perhaps re 1 to 3 scans per peak ? ideally minimum of 10scans per peak
see accuracy proven below for typical FAST GC . . . obvious a simulated chromatogram or perhaps on a high speed TOC GC/MS sytsem and “idealised”
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Speed Relevance from Process Control GC Perspective
Cost savings re finesse of production control raw materials product throughput etc - invaluable
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Who would Use Calidus FastGC Enviro Labs Idealfor field or lab preliminary scanning tool . . . for follow-up detailed High(er) resolution of target samples by GC and/or GC/MS 4metres (max of Calidus) 0.1mmID MXT Nt 32,000 = 15metres 0.25mm Peak Resolution re Packed GC Column 30ft of 1/8”OD ~Nt 16,000
Huge potential; savings for work intensive laboratories
Process Control GC many application can run at 20 times the speed Economies of scale with finer control of process plants
2D-GC Applications Heart Cutting eg First seperaton om a non-polar column with overlapping peaks separated on a polar column all in-line . . . on-line. - can be equivalent to a single column separation with “millions of plates”
Fast GC AND TSE increases LOD by refocusing “broad” peaks/ post column . . . x14 to x40; particularly for many volatiles on a (mini-) TCD detector requires air compressoer and “vortex” cooling
DISADVANTAGES Injected on-column Sample Capacity is less and requires a Split sample BUT Sharper Peaks means LOD Limit of detection so ~ the same
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FAST GC high speed . . . separation in <120seconds NOT minutes AND High Temperature C60+ or higher
far better than any process Control GC anywhere “proven” to ASTM D2887 standards
Process Control - SIMDIST D2887
“Approved” to ASTM Standards Calidus certification . . . pending
18x times Faster
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Calidus 2D GC + TSE
a simple powerful 2D-GC gas separation - heartcut to 2nd column - 4mins ASK for details
with TSE capability
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TSE ( Targetted Signal Enhancement ) Vortex Cooling - requires 80psi 4cfm air compressor but up to x75 increase in sensitivity for TCD for Process GC : 6.5x3.x2” preferably separate or GC oven - sub ppM LOD for CO2, CO, C2+ HCs, water, S-Compounds (?) potentially N2O (???) application to Lab GC ???? maybe ?
Modularity Detectors - micro FID & microTCD; more coming Injectors : SSIS and Aout FasSampling Vlaves Valve Oven Module
(relatively) Simple add-on . . . upgrade
Transportable, robust design & compatible with Field use
some Theory Re UltraFAST GC - Increasing GC Speed some Tips PDF The Rise and Fall of Expertise in Gas Chromatography(LCGC) PDF Pivotal Article JofC 2004 195-267PDF
for isothermal GC Nt=5.54(Tr/W50)^2; Neff=5.54((Tr-Ta)/W50)^2 k=(Tr-Ta(/Ta Neff=N t x (k/k+1) So. . . R=1/4SqRt(Neff)
for Temp Prog GC
Fast GC Data (?) - evidence suggest 5m 0.1mm needs >300Hz Data System
Characteristic / ID
0.10mm
0.15mm
0.18mm
0.25mm
0.32mm
0.53mm
Helium Flow (20-30cm/sec)
0.16
0.3
0.3
0.7
1.2
2.6
H2 Flow @40-60cm/csec
0.32
0.6
0.6
1.4
2.4
5.2
Sample Capacity
<10ng
<40
<50
50-100
400-500
1000-2000
Theoretical Plates/metre
8000
4000
3500
3200
2500
1800
Calidus(Max) 4m=32,000
10m=32000
15m=37500
TZ (Trenzzahl)
(5m 0.1mm) 24(0.35s/300Hz >10(0.11sec)
20
50micron FS GC columns are NOW available
but depends on heat rate , actual w50 and Hz*
*some GCs are h’ware limited
many OEMs wll NOT publish data because of this some even refer to this as being “academic”
124p PDF 14mB
