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For Analyses at Extreme pH Conditions
By Becky Wittrig, Ph.D., HPLC Product Marketing Manager, Frank Dorman Ph.D., HPLC Innovations Manager, Rick Lake, Pharmaceutical Innovations Chemist,
Vernon Bartlett, HPLC Innovations Scientist, Bruce Albright, HPLC Innovations Chemist, and Randy Romesberg, HPLC Innovations Chemist
We are pleased to introduce pHidelity™ pH-stable HPLC columns, designed for analyses that require,
or benefit from, extreme pH conditions. pHidelity™ columns incorporate a proprietary barrier layer
that protects the base silica particle, and a secondary layer that provides the functional stationary phase
ligand. pHidelity™ columns can be used routinely up to pH 12 – a significant improvement over the
typical pH 2.5 to 7.5 range for silica-based materials. pHidelity™ columns give you more control over
analyte retention and resolution; mobile phase pH can be increased to enhance retention of basic ana-
lytes – without sacrificing column lifetime.
Continued on page 4.
New
pHidelity™
pH-Stable HPLC Columns
Pharmaceutical