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The Cliquid® Drug Screen & Quant Software automates this test and generates
a verification report which highlights failures. Peak area, peak shape, retention
time reproducibility, fragmentation, and library search function all are evalu-
ated through the software by comparing the test mix data to expected results.
For example, full scan linear ion trap MS/MS data for diazepam and caffeine
are compared to the library to assess fragmentation. A mass spectral match of
80% or more must be achieved to pass this portion of the system suitability
test. Otherwise, the failure will be highlighted on the automated report.
Analyzing this system suitability mix for drug analysis on a regular basis
assures system performance, improves data quality, increases sample through-
put, and simplifies troubleshooting. Moreover, the Cliquid® Drug Screen &
Quant Software for Routine Forensic Toxicology enables nonexpert
LC/MS/MS users to employ this system suitability test with little effort.
Acknowledgement
Method and data supplied by Applied Biosystems.
References
H. El Arbi, T. Sasaki, A. Schreiber, K. Sellers, K. Herwehe. Development of an LC/MS/MS System Suitability Test
for Forensic Toxicology Applications. Applied Biosystems/MDS Sciex, 2007.
amiodarone
10µg/mL
amphetamine
10
caffeine
10
codeine
10
diazepam
10
doxepine
10
haloperidol
1
morphine
10
Forensic Drug Screen Test Mixture
In P&T methanol, 1mL/ampul
cat. # 36340
(ea.)
D5-diazepam
D5-doxepine
Forensic Drug Screen Internal Standard
10µg/mL each in P&T methanol, 10mL/ampul
cat. # 36341
(ea.)
Allure® PFP Propyl Columns (USP L43)
Excellent Columns for LC/MS and ELSD
Physical Characteristics:
5µm Column, 2.1mm
cat. #
price
30mm
9169532
50mm
9169552
5µm Column, 3.2mm
cat. #
price
30mm
9169533
50mm
9169553
5µm Column, 2.1mm
cat. #
price
30mm (with Trident Inlet Fitting)
9169532-700
50mm (with Trident Inlet Fitting)
9169552-700
5µm Column, 3.2mm
cat. #
price
30mm (with Trident Inlet Fitting)
9169533-700
50mm (with Trident Inlet Fitting)
9169553-700
particle size: 5µm, spherical
pore size: 60Å
carbon load: 17%
endcap: fully endcapped
pH range: 2.5 to 7.5
temperature limit: 80°C
ABI/SCIEX Cliquid® Drug Screen Mix
Trident Direct Guard Cartridge System
Easy to Use, Low Dead Volume—The Ultimate
Combination of Convenience and Column
Protection
Description
qty. cat.#
price
10mm guard cartridge holder with filter
ea. 25084
20mm guard cartridge holder with filter
ea. 25086
Connection tip for Waters-style end fittings ea. 25088
PEEK tip standard fittings
ea. 25087
Trident Direct 10mm
guard cartridge holder
with filter
Protection against
particulate matter and
moderate protection
against irreversibly
adsorbed compounds.
Trident Direct 20mm
guard cartridge holder
with filter
Protection against
particulate matter and
maximum protection
against irreversibly
adsorbed compounds.
Allure
®
PFP Propyl Guard Cartridges qty.
cat. #
price
10 x 2.1mm
3-pk.
916950212
10 x 4.0mm
3-pk.
916950210
20 x 2.1mm
2-pk.
916950222
20 x 4.0mm
2-pk.
916950220
ordering
note
For other dimensions of these columns, visit our website at
www.restek.com.
Use this system suitability mix for drug
analyses to assure system performance
and simplify troubleshooting.
Get More!
Clinical/Forensics/Toxicology
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