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Analytical Comparison – Impurity Analysis
Analysis Time:
Equilibration Time:
Solvent Usage:
ACN Usage:
Ultra II Aromax
3µm
150 x 3.2mm
Allure C18 (USP)
5µm
250 x 4.6mm
5µm
150 x3.2 mm
2.2µm
3.0mm x 50 mm
45 min.
15 min.
8 min.
4 min.
15 min.
4 min.
6 min.
1.5 min.
90mL
38mL
17mL
6.6mL
Yes
No
No
No
Method Optimized by Selecting the Best Stationary Phase, then Run Conditions!
• 11 fold reduction in analysis time
• 14 fold reduction in mobile phase consumption
• Select particle size based on HPLC system
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