Allure
TM
PFPP -UsesHighest
%Organic forBasicAnalytes
l
PFPP allows theuse ofmuch
more organic inM.P. to give
the same amount of retention
of conventional phases.
l
This allows increased
sensitivity inLC/MS, LC/IR,
andLC/ELSD of 600%or
more.
l
5mMNH
4
OAc, pH4.5:ACN;
30x 2.1mm; 0.4mL/min
RetentionBehavior ofAmitriptyline
0
50
100
0
50
100
%ACN
k
C4
CN
OH
PFP
%ACN
k’
50 100
Amit iptyli e
DataCourtesyof Shane
Needham, Pfizer Inc
