RtxPresentations07 - page 498-499

Allure
TM
C18VS. Conventional
C18Phase -Neutral Steroids
A
T
l
HigherC load allows
use of 12%more
organic; Results in a
26% increase in
LC/MS sensitivity
l
1. Deoxycorticoster-
one (DCC)Acetate, 2.
DCCGlucoside, 3.
DCC; 0.4mL/min;
Pos. ionESI-TOF
Conventional C18 Allure
Conven
TM
TM
C18
12%C
27%C
50 x 2.1mm
Data courtesy of ShaneNeedham, Pfizer Inc
1
1
2
2
3
3
H
2
O:MeOH (40:60) H
2
O:MeOH (33:67)
1...,478-479,480-481,482-483,484-485,486-487,488-489,490-491,492-493,494-495,496-497 500-501,502-503,504-505,506-507,508-509,510-511,512-513,514-515,516-517,518-519,...
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