Allure
TM
C18VS. Conventional
C18Phase -Neutral Steroids
A
T
l
HigherC load allows
use of 12%more
organic; Results in a
26% increase in
LC/MS sensitivity
l
1. Deoxycorticoster-
one (DCC)Acetate, 2.
DCCGlucoside, 3.
DCC; 0.4mL/min;
Pos. ionESI-TOF
Conventional C18 Allure
Conven
TM
TM
C18
12%C
27%C
50 x 2.1mm
Data courtesy of ShaneNeedham, Pfizer Inc
1
1
2
2
3
3
H
2
O:MeOH (40:60) H
2
O:MeOH (33:67)