R e s t e k
Alpha (Selectivity) inFast LC
•
Alpha has the greatest influence over the
separation efficiency.
•
Small changes inAlpha can lead to dramatic
increase in resolution.
•
Small changes inAlpha from 1-2 have the
greatest influence on resolution.
•
Additional increases inAlpha can be realized by
taking advantage of other chemical and physical
properties of the analyte,mobile phase
composition, and the stationary phase.
