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2
The Rt-
β
DEXsm and Rt-
β
DEXse
chiral capillary columns offer
extensive enantiomeric separation
of monoterpenes, monoterpene
alcohols, and monoterpene ketones
that cannot be matched by
permethylated
β
-cyclodextrin
columns. Rt-
β
DEXsp and Rt-
β
DEXsa are secondary columns
that best resolve specific flavor and
fragrance chiral components. The
Rt-
β
DEXcst provides excellent
resolution of some complex flavor
compounds and has demonstrated
great potential with pharmaceutical
substances as well.
Index:
Definitions of Chirality and
Chiral Chromatography ......
3
Chiral Columns Offer
Unique Selectivity ...............
5
Optimization of Chiral
Separations .....................
10
Chiral Specific Applications
of Essential Oils, Flavors, and
Pharmaceuticals ..............
14
A team of researchers at the
University of Neuchâtel
developed
β
-cyclodextrins with
superb enantiomeric
selectivity. They joined forces
withRestek, amanufacturer of
top quality columns, to provide
a unique line of commercially
available
β
-cyclodextrin
stationary phases with
enhanced capabilities for
chiral capillary gas
chromatography.
Dr. Raphael Tabacchi
Born in Ticino, Switzerland,
Dr. Tabacchi has been a
professor for Analytical and
Organic Structure at the
University of Neuchâtel,
Switzerland, since 1978. His
research interests focused
upon natural product
chemistry, and development
of HPLC andGC stationary
phases. He has developed
β
-
cyclodextrins with unique
substitutions to create novel
chiral phases for capillary
GC.
Dr. Georges Claude Saturnin
Born in St. Joseph,
Martinique, Dr. Saturnin
became a Senior Assistant
and Assistant Professor in
1990 at the University of
Neuchâtel. He is involved in
the development of HPLC
phases. His focus is the
synthesis of these new
cyclodextrin materials that
characterize the new chiral
columns.
Lori Bitzer
After completing her
Chemistry degree at West
Virginia University in 1995,
Lori joined Restek as a Fused
Silica Manufacturing
Chemist. She is involvedwith
the design and production of
new products including
capillary chiral columns. Lori
ensures product quality and
consistency that are
characteristic of all Restek
products.
Sherry Sponsler
Sherry is an Applications
Chemist and has beenwith
Restek since 1990. She
conducts method and product
development for analysis of
foods, flavors and fragrances,
as well as some pharmaceuti-
cal samples. Frequent
communication with
customers has helped Sherry
to identify many important
chiral applications in these
industries. She has demon-
stratedmany of these key
separations, especially for
fragrances and amphet-
amines, using the new
cyclodextrin capillary
columns.
Maurus Biedermann
Maurus has beenwithDr.
Konrad Grob’s GC/LCGC
group at the Kantonales
Laboratory Zurich (Official
Food Control Authority in
Switzerland) since 1990 and
has participated in the
development of several
LCGCmethods for food
analysis. During his
sabbatical at Restek, he
demonstrated the ability of
these new and unique chiral
phases for many applications
such as the authenticity of
essential oils, “natural”
flavor extracts, and the
analysis of drugs for
enantiomeric composition.
Claire-Lise Porret
Born in Neuchâtel, Switzer-
land, Ms. Porret was
previously a technician at
Nestlé and joinedDr.
Tabacchi’s team in 1991. She
is also involved in the
synthesis of organic
compounds and with the
development of GC and
HPLC stationary phases.
restek
CORPORATION
