ADV06-15_1-412

Clin ical/Forensics

Figure 3

An Rxi™-Sms column prov ides the symmetric peaks and

resolution needed for reliable confi rmation of GHB.

Column:

Rxi™-Sms 30m, 0.25mm !D, 0.251-/m(cat.# 13423)

Sample:

50l-/g/ml

gamma-butyrolactone(GBl) and251-/g/ ml

gamma-butyrolactone-d6 (GBl-d6)inmethanol

Inj.:

lI-Il split(1:10), 4mmSiltek" treatedsinglegooseneck

inlet liner (cat.# 20798)

In],

temp.:

250°C

Carrier gas:

Flowrate:

helium,constant flow

1ml /min.

Oven ternp.:

40°C(3 min.)to 300°C

25°C/min.(hold 5min.)

Det:

Transfer line

temp.:

280°C

Scan range:

35·200 amu

Ionization:

Mode:

scan

GBl ·d6 (rn/z

92)

2. GBl (rn/ z

86)

GC.PHOOS6S

",:..

I .•

.1"

"I, .

10' , • •

.I~

.1. ..

.JI .

nT" " ."

4.5

5.0

5.5

6.0

Because this methodology for analyzing GHB in

biofluid s employs samp le introduction through a

headspace technique, the need for injector and col

umn maintenance is dramatically reduced. The

use of an existing headspace GC system for blood

alcohol analysis eliminates the need for additiona l

equipmen t and allows rapid and reliable screen

ing, using the same Rtx®-BACl or Rtx®-BAC2 col

umn. For positive results, an Rxi™-Sms column in

GC/MS

system provides accurate con firmation

and quantification of GHB.

Reference

1 l eBeau, M.A., M.A. Montgomery, M.l Miller,and S.G. Burmeister,

Anal.Toxicol. 24 (6): 421-428(Sept.2000).

Rtx@-BAC1 Columns (fused silica)

film)

temp. limits

length cal

price

9.32mm L 80 -20 to

2401260°C

30-Meter 18003 $485

0.53mm 3.00 -20 to

2401260°C

30-Meter 18001 $510

Rtx@·BAC2 Columns (fused silica)

film)

temp.limits

length cal

price

0.32mm 1.20 -20 to

2401260°C

30-Meter 18002 $485

0.53mm 2.00 -20 to

2401260°C

30-Meter 18000 $510

Figure 4

Overlay of extracted ion chromatograms

for GBLand GBL-d6.

Column:

Sample:

Inj.:

Inj. temp.:

Carrier gas:

Flow rate:

Oven temp.:

Det:

Transfer line

temp.:

Scan range:

Ionization:

Mode:

Rxi™-5ms 30m, 0.25mm!D, 0.251-/m (cat.# 13423)

50l-/g/ml

gamma-butyrolactone (GBl) and 251-/g/ ml gamma

butyrolactone-d6 (GBl -d6) inmethanol

lI-Il split (1:10), 4mmSiltek" treated single gooseneckinlet

liner (cat.# 20798-214.1)

250°C

helium, constant flow

1ml / min.

40°C(3min.)to300°C

25°C/min. (hold5 min.)

280°C

35-200 amu

scan

GBl-d6

(m/z

92)

2. GBl (m/z B6)

1, ,11

Ile.

ol. L

GCPH00869

4.0

4.5

5.0

5.5

free

literatur e

6.5

Clinical/Forensics Products

Applications for GC

HPlC

(2006/07

Edition)

This 64-page catalog presents a wealth of information about clinical and forensic analyses by GC

and HPl C. Clinical applications include analgesics, antihistamines, cardiac medications, CNS depres

sants, cold

sinus medications, steroids, and more; forensic applications include arson acceler

ants, anesthetics, barbiturates, blood alcohol, butyrolactone, cannabinoids, cocaine, opiates, and

more. I ncludes references to many additional free Restek publications that discuss specific subjects

in detail. lit cat# 59989A

2006.03

• 5 •

Rxi™-5ms Columns (fused silica)

(Crossbond" 5%diphenyl

95%dimethyl polysiloxane)

dffllm)

temp. limits

length cat

price

0.18mm 0.18 ·60 to

330/350°C

20-Meter 13402 $370

0.18mm 0.36 -60 to

330/350°C

20-Meter 13411 $370

0.20mm 0.33 -60 to

330/350°C

12-Meter 13497 $230

0.20mm 0.33 -60 to

330/350°C

25-Meter 13498 $365

0.20mm 0.33 -60 to

330/350°C

50-Meter 13499 $630

0.25mm 0.25 -60 to

330/350°C

I S-Meter 13420

0.25mm 0.25 -60 to

330/350°C

30-Meter 13423 $435

0.25mm 0.25 -60 to

330/350°C

60-Meter 13426 $780

0.25mm 0.50 ·60 to

330/350°C

I S-Meter 13435 $260

0.25mm 0.50 -60 to

330/350°C

30-Meter 13438 $435

0.25mm 0.50 -60 to

330/350°C

60-Meter 13441 $780

0.25mm LOO

-60 to

330/350°C

15·Meter 13450 $260

0.25mm l.00 -60 to

330/350°C

30-Meter 13453 $435

0.25mm LOO -60 to

330/350°C

60-Meter 13456 $780

Universal "Y" Press-Tlqht" Connectors

alternative method of performing dual-column

confirmational analyses!

20405

Descri lion

Universal "Y" Press-Tight@Connector

DeactivatedUniversal

"Y" Press-Ti ht@Connector

20405-261

$62

iltek~

Treated Universal

"Y" Press-

Tight~

Connector

20485

$63

For a complete list of connectors, refer to our catalog or website.

800-356-1688 • www.rest

ek.com

Website :

www.chromtech.net.au

E-mail :

info@chromatech.net.au

TelNo : 03 9762 2034 . . . in AUSTRALIA