2014-RestekAPPS-Index - page 26

InnovativeChromatographyProducts
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Asmedical marijuana ismore frequently prescribed, patient safetymust be ensured. Pesticide residue testing is
an important part of assuring safe product is dispensed, but analysis can be extremely challenging due tomatrix
complexity. The use of QuEChERS, cartridge SPE cleanup, and GCxGC-TOFMS as presented here produces
high-quality quantitative data for this difficult analysis.
High-Quality Analysis of Pesticides in Cannabis Using QuEChERS,
Cartridge SPE Cleanup, and GCxGC-TOFMS
Proper GC column choice is essential for accurate and robust medical cannabis potency testing. Using an
Rxi -35Sil MS column under the instrument conditions shown here allows fast, accurate reporting of
cannabichromene and cannabidiol inmedical marijuana samples.
Don’t Overestimate Cannabidiol During Medical Cannabis Potency
Testing by Gas Chromatography
Raptor™ LC columns combine the speed of superficially porous particles (i.e., SPP or “core-shell”) with
the resolution of highly selective USLC® technology. Featuring Restek'smost popular LC stationary
phase, the rugged Raptor™ Biphenyl is extremely useful for fast separations in bioanalytical testing
applications like drug andmetabolite analyses, especially those that require amass spectrometer (MS).
(PDF - 5050kB)
Raptor Biphenyl LC Columns Brochure
When we engineered our superficially porous particle (SPP or "core-shell") Raptor™ LC columns, we
developed the bonding chemistries that are best suited to both the SPP construction and our highly
selective USLC® phases. But we didn't stop here. Take a closer look at a new species as we dissect the
upgraded hardware and new, proprietary packing techniques behind Raptor™ LC columns and Raptor™
EXP® guard columns. (PDF - 571kB)
Dissecting Raptor™ LC Columns: A closer look at a new species
Dr. Radomír Čabala, Head of the Toxicology Department at the General University Hospital in Prague,
presents work on the potential utility of GC-TOFMS analysis of cellular fatty acidmethyl esters (FAMEs)
in identifying clinically relevant bacteria.
Characterizing Cellular Fatty Acid Methyl Ester (FAME) Profiles to
Identify Bacteria Using Gas Chromatography
Unlike C18 columns, Ultra IBD (intrinsically base deactivated) columns can interact in normal phase
modewith analytes that possess charged functional groups, providing greater versatility for LC-MS
analyses. Excellent peak shape in either normal phasemode or reversed phasemode increases
sensitivity and improves quantification. The 4-page note shows example analyses of penicillins and
cephalosporins. (PDF - 987kB)
Excellent LC-MS Separation of Penicillins and Cephalosporins Using
Ultra IBD Columns
Analyze volatile compounds and polar analytes with greater confidence using Rxi®-624Sil MS columns.
Optimized selectivity, higher inertness, and lower bleed result in reliable separations and accurate,
trace-level determinations. Includes environmental and pharmaceutical applications. (PDF - 3111kB)
Rxi®-624Sil MS Columns—Exceptionally Inert, Low Bleed Columns
for Volatiles Analysis
USLC™ columns and this guidewill help you easily choose the right stationary phase to target nearly
any analyte in reversed phase or HILICmethod development. It will also help you adjust yourmobile
phase to further improve results without guesswork or wasted time. (PDF - 1682kB)
USLC™ Column Selection &Mobile Phase Adjustment Guide
Column selectivity has themost significant influence on chromatographic peak separation, or
resolution, so choosing the right column can greatly speed up HPLC and UHPLCmethod development.
In this article, we discuss column choice and identify a set of just 4 stationary phases—Restek’s USLC
column set—that encompasses thewidest range of reversed phase selectivity available today.
USLC Columns Put the Right Tools in Your LCMethod Development
Toolbox
Pharmaceutical
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