4
Figure 3
Sky™ liners are completely passivated. Even when using wool, peak shape for highly active underiva-
tized amphetamine is excellent.
Sky™ liners reliably provide excellent
peak shape and response for active
basic compounds.
Comprehensive Deactivation Assures Excellent Peak Shape
In addition to providing excellent results for reactive pesticides and acidic compounds, Sky™ inlet liners are also highly inert
to active basic compounds, such as underivatized amphetamines. The exceptional inertness of Sky™ liners produces much bet-
ter peak shape than is typically seen on other liners, resulting in simpler quantification and more accurate results (Figure 3).
GC_CF1151
Amphetamine
Column Rxi
®
-5Sil MS, 30 m, 0.25 mm ID, 0.25 µm (cat.#
13623); Sample ~10 µg/mL amphetamine in 1-chlorobu-
tane; Injection Inj. Vol.: 1 µL splitless (hold 1 min.); Liner:
Comparison of Sky™ Single Taper Gooseneck with Wool
(cat.# 23303.5) and SGE Single Taper Gooseneck with Wool
(cat.# 092019); Inj. Temp.: 250 °C.
Restek Sky™ Inlet Liners
SGE
Figure 2
The state-of-the-art deactivation used for Sky™ liners with wool results in higher responses for active
acid compounds, such as 2,4-DNP.
Greater Inertness Results in Higher Analyte Response
Another common probe used to illustrate inertness is 2,4-dinitrophenol (2,4-DNP), which functions as an indicator of acid
compound interactions. It is used to monitor system suitability in semivolatiles methods, which benefit from the use of wool
to assist in sample vaporization. As shown in Figure 2, the response of 2,4-DNP with the Sky™ inlet liner, even at low concen-
trations, is superior to a competitor's liner. The Agilent liner with wool has active sites that adsorb 2,4-DNP and reduce its
response. In contrast an excellent response is achieved using the Sky™ liner, even in the presence of wool.
GC_EV1204
Restek Sky
Inlet Liner
Single taper
gooseneck
with wool
Agilent
Single taper
gooseneck
with wool
1
2
1
2, 4-DNP RF=0.29
2, 4-DNP RF=0.03
Increase the response of active
analytes with inert Sky™ inlet
liners!
Column Rxi
®
-5Sil MS, 15 m, 0.25 mm ID, 0.25 µm (cat.#
13620); Sample 10 µg/mL each 2,4-dinitrophenol and ace-
naphthene standard in methylene chloride; Injection Inj. Vol.:
1 µL splitless (hold 1 min.); Liner: Comparison of Sky™ Single
Taper Gooseneck Inlet Liner with Wool (cat.# 23303.5) and
Agilent Single Taper Gooseneck Inlet Liner with Wool (cat.#
5062-3587); Inj. Temp.: 250 °C.
Peaks
1. Acenaphthene (IS)
2. 2,4-DNP
2
Simple Solutions:
Inert Sky™ Inlet Liners Improve Accuracy and Precision for a Wide Range of Analytes
2013
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