Figure2:
Dual columnanalysisof abused inhalants.
4
Time (min)
Time (min)
2
0
4
6
8
10
12
1 2 3
4
5
6
7
8
9
10 11
12
13
14
15
16
17, 18
19
2
0
4
6
8
10
12
1
4
2
5
8, 7, 3
6
9
10
11
12
13
14
15
16
17, 18
19
GC_CF1162
Columns: Rtx®-BACPlus1, 30m,0.32mm ID, 1.8μm (cat.#18004)andRtx®-BACPlus2, 30m,0.32mm ID,0.6μm (cat.#18006)usingRxi®guardcolumn, 5m,0.32mm ID (cat.#10039)with
Universal “Y”Press-Tight®connector (cat.#20405-261); Sample: 50μg/mLeach inhalant inwater; Injection: headspace-loopsplit (split ratio50:1); Liner: 1mm straight inlet liner (cat.#20972);
Headspace-Loop: Inj.PortTemp.:220 °C; Instrument: TekmarHT3; Inj. Time: 3min;TransferLineTemp.: 125 °C;ValveOvenTemp.: 125 °C;SampleTemp.: 70 °C;SampleEquil. Time:5min;VialPressure:
30psi; PressurizeTime: 2min; LoopPressure: 20psi; LoopFill Time: 1min;OvenTemp:40 °C (hold4min) to120 °Cat10 °C/min (hold0min);CarrierGas:He, constantflow; LinearVelocity: 50cm/
sec;Detector: FID@240 °C;Make-upGas:N
2
, 30mL/min; Instrument:Agilent/HP6890GC;NotesTheRtx®-BACPlus1andPlus2columnswereconnected to the injectionportusinga~12 inch
sectionofguardcolumnbetween the injectionportand theUniversalYPress-Tight®connector.Headspaceconcentrator courtesyofTeledyneTekmar,Mason,OH.
Peaks
BACPlus1RT (min)
BACPlus2RT (min)
1. Methanol
1.340
1.230
2. Ethanol
1.694
1.470
3. Isopropanol
2.072
1.660
4. Diethyl ether
2.149
1.334
5. Acetone
2.256
1.589
6. Methylenechloride
2.405
1.703
7. MTBE
3.185
1.660
8. Hexane
3.683
1.660
9. Chloroform
3.956
2.667
10. MEK
4.210
2.543
Rtx®-BACPlus columns canbeused forother low temperatureapplications for volatileorganiccompounds, due to theirunique
selectivity, retention, and inertness. For example, in theanalysisof abused inhalants inFigure2,most compoundsare resolvedbe-
tween thecolumnswith several elutionorder changes for confirmation. Inaddition, excellentpeak shapesareobserved. As shown
inFigures3and4, Rtx®-BACPlus columns canalsobeused for singlecolumnapplications, suchasglycolsorgamma-butyrolactone
(GBL),which isaderivatized formofgamma-hydroxybutyrate (GHB).The lowbleedcharacterof thesecolumnsalsomakes them
useful formass spectrometryapplications.
Peaks
BACPlus1RT (min)
BACPlus2RT (min)
11. Ethyl acetate
4.54
2.414
12. Benzene
5.390
2.883
13. Trichloroethylene
6.306
3.522
14. MIBK
8.101
5.775
15. Toluene
8.162
5.440
16. Ethylbenzene
10.286
7.681
17.
m
-Xylene
10.487
7.879
18.
p
-Xylene
10.487
7.879
19.
o
-Xylene
10.990
8.467
OtherApplications
Rtx®-BACPlus1
Rtx®-BACPlus2
