Page 24 - PC-TECHAll-11 65p

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15
LC-05
LC-05 Auto Injector
LC-05
auto injector is for automatic introduction of samples from a
fixed source. Typical applications are online monitoring. It enables
a normal HPLC to fulfill tasks that cannot be done using a HPLC
auto sampler.
By adding a valve based fraction collector, large scale
purification can be achieved using an analytical scale HPLC.
LC-05 Auto Injector is designed to work with any type of HPLC
instruments. Its versatile interface makes the integration easy
and fast. The user friendly and powerful software provides
highly automatic and reliable control.
1. Working principle
The injector consists of a divert valve,
a load pump, a high-pressure switch
valve, and the control software. The
divert valve makes selection between
two sources for injection. For on-line
analysis, one source can be the sample
and the other source can be the
calibration solution. In case of repeated
injection for large scale purification,
the two sources can be two samples.
The load pump is used to deliver
sample to the sample loop. The pump
can deliver very accurate volume,
since the volume per cycle is fixed
and the number of cycles is controlled
by the software. The switch valve is
used to connect the HPLC pump to the
sample loop for injection.
The diagram of the software not only
demonstrates the working principle
but also serves as a graphical user
interface. The software provides two
types of control for the injector. The
components of the injector can be
directly switched by clicking on the
The user interface of the control software
relevant icons in the diagram. A second click can stop the pump. For a more automatic control,
methods or sequence can be used. The software monitors the status of the injector and the HPLC
regularly. The status is reflected in the diagram for easy observation. For example, when the switch