Inertness comparison (basic compounds): primary, secondary, and tertiary amines on an Rxi®-624Sil MS
column.
46 www.restek.com
Rxi®-624Sil MS Structure
X
Y
Z
Si O
R
CH
3
CH
3
CH
3
C N
CH
3
Si O
O
CH
3
CH
3
Si
CH
3
CH
3
Si
similar
phases
DB-624, HP-624, VF-624, BP-624, ZB-624,
AT-624, 007-1301, G43R
Rxi®-624Sil MS Columns
(fused silica)
(midpolarity Crossbond® silarylene phase; equivalent to 6% cyanopropylphenyl/
94% dimethyl arylene polysiloxane)
• Low bleed, high thermal stability column—maximum temperatures up to 320 °C.
• Inert—excellent peak shape for a wide range of compounds, including acidic and
basic compounds.
• Selective—highly selective for residual solvents, great choice for USP<467>.
• Manufactured for column-to-column reproducibility—well-suited for validated
methods.
Column
Rxi
®
-624SilMS, 30 m, 0.32 mm ID, 1.8 µm (cat.# 13870)
Sample
Diluent:
DMSO
Conc.:
100 µg/mL
Injection
Inj. Vol.:
1 µL split (split ratio 20:1)
Liner:
5mm Single Gooseneck with Wool (cat.# 22973-200.1)
Inj. Temp.:
250 °C
Oven
Oven Temp:
50 °C (hold 1 min.) to 200 °C at 20 °C/min. (hold 5 min.)
Carrier Gas He, constant flow
Linear Velocity: 37 cm/sec.
Detector
FID @ 250 °C
Instrument Agilent/HP6890 GC
GC_PH1162
Peaks
Conc.
(µg/mL)
1. Isopropylamine
100
2. Diethylamine
100
3. Triethylamine
100
Highly inert Rxi®-624Sil MS columns
give excellent peak symmetry for
active primary amines.
NEW!
ID
df
temp. limits
20-Meter
30-Meter
60-Meter
0.18mm 1.00µm -20 to 300/320°C 13865
0.25mm 1.40µm -20 to 300/320°C
13868
0.32mm 1.80µm -20 to 300/320°C
13870
13872
0.53mm 3.00µm -20 to 280/300°C
13871
free
literature
Rxi®-624Sil MS: The "Go To" GC Column for Fast,
Effective Volatile Impurities Method Development
Download your free copy from
www.restek.com
lit. cat.# PHFL1245
Website : www.chromtech.net.au E-mail : info@chromtech.net.au TelNo : 03 9762 2034 . . . in AUSTRALIA Mar