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Membrane Solutions LLC
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Silica Base
Chrompure
@-c
CI8 -ne
18
Partkal Size 40-60
urn
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
no
Carbon(COfo)
17%
• Non-endcapped bonded phase
that enables the silica surface to be
more active
• Moderately nonpolar and polar secondary interactions
• Enhanced the retenti on of polar and basic ccrnpounds than C1S
Chrompure C18
@-C
1 8
Chrompure C8
Chrompure
eN
fSiL–
....,
~N
Chrompure PSA
@)~1{~NH2
Partkal Size 40-60
urn
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
no
Carbon(C%)
17%
Partical Size 40-60
um
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
yes
Carbon(COfo)
11%
Partical Size 40-60
urn
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
yes
Carbon(COfo)
65%
Partical Size 40-60
um
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
No
Carbon(COfo)
7%
pI<,:
10.1 and 10.9
Organic anIalytes extraction
C1S has the broadest spectrum of
retention among bonded silica s o-bents, since it retains most organic
analytes from aqueoos matrices, when the corrp cunds of interest vaty
widely in structure
Desalting
When analyzing small t o intermediate molecules,
Chrempure C1S can be used for desalting aquecus matrices pri ce to
icc exchange, as salts pass thrcugh the sa-bent unretained
Moderate Hydrophobicity
separating a wide range of compounds
and replace C1S when too strongly retention 00 C1S
Simultaneous Extraction:
fat- and wat er-solution vitamins from
human serum and herbicides, fungicides, pesticides frem waste
• Both
normal and reversed-phase
chrematography
• Less polar cempared t o silica and less hydrophobic compared t o
C1S and CS
• Usually used to extract acidic, neutral, and basic corrp ounds frem
aqueous soluti ons
• Similar selectivity t o Chrempure NH2
• Strong affinity and high capacity fa- removing fatty acids,
crganic
acids, and some polar pigments and sugars when conducting
multi-residue pesticide analysis in foods
• Excellent sa-bent fa-
chelation
3
Chrompure NH
2
~NH2
Partical Size 40-60l-lill
Silica Base
irregular shaped
Pore Size
52-68A
Endcapped
No
Carbon(C%)
35%
pKa:
9.8
L..-__----'
• Amino propyl phase,
bcth hydrogen bending and anion exchange
• Weaker anion exchanger retention of very strong anicns such as
sulfcnic acids which may be retained irreversibly on SAX
• Separate peptides, drugs and metabolites from physiological fluids,
and extraction of mono- and polysaccharides, steroids, cholesterol
and triglycerides
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