Basic HTML Version
O
Si
OH
Si
Si
O
O
O
O
Si O
O Si
OSi
O
Si
Si
O O
O
O
Si
O
Si
O
Si
Si
O
O
Si
O
Si
Si
O
O OO
Si
O Si
O
O
O
O Si
Si
Si
O O
O
O
Si
OSi
O Si
Si O
O
O
O
O
O
Si
O
Si
Si
O
O
O
O
O
O
Si
OSi
O
Si
Si
OH
O
O
O Si
O
Si
O
Si
OO
O
O
Si
OH
O
TMS
化
1
2
3
Si
X
Si
O X
X
CH
3
CH
3
n
Particle size
(
μ
m)
Pore diameter
(nm)
Specific surface area
(m
2
/g)
Carbon content
(%)
Bonded phase pH range
Sunniest C18
3 and 5
12
340
16
C18
1.5 - 10
Sunniest RP-AQUA 3 and 5
12
340
16
Near C18
2 - 8
Sunniest C8
3 and 5
12
340
10
C8
1.5 - 9
Fig. 2 Schematic diagram of bonding of novel silyl-
reagent on silica surface
A Novel Bonding Technique
(patent pending)
An unique trifunctional silyl-reagent was developed as shown
in Fig. 1. This silyl-reagent can bond with any silanol groups
on silica surface as shown in Fig.2 because it can expand
and contract by itself. This technique can make residual
silanol groups on C18 stationary phase to be the least
amount.
Finally an end-capping was done with trimethylsilyl-reagent
(TMS).
n: 1, 2 , 3 or 4
X: Cl, OCH
3
, OCH
2
CH
3
etc.
Fig. 1 Novel C18 reagent
Features
★
Little residual silanol groups by an
unique bonding technique
★
Excellent stability, especially under
acidic pH conditions
★
Sharp peak shape for acidic, basic
and chelating compounds
★
RP-AQUA is available under 100%
aqueous conditions, and shows
enhanced retention of polar compounds.
Characteristics of Sunniest
Website : www.chromtech.net.au E-mail : info@chromtech.net.au telNo : 03 9762 2034 . . . in AUSTRALIA