Membrane Solutions LLC
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Silica Base
Chrompure
@-c
CI8 -ne
18
Partkal Size 40-60
urn
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
no
Carbon(COfo)
17%
• Non-endcapped bonded phase
that enables the silica surface to be
more active
• Moderately nonpolar and polar secondary interactions
• Enhanced the retenti on of polar and basic ccrnpounds than C1S
Chrompure C18
@-C
1 8
Chrompure C8
Chrompure
eN
fSiL–
....,
~N
Chrompure PSA
@)~1{~NH2
Partkal Size 40-60
urn
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
no
Carbon(C%)
17%
Partical Size 40-60
um
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
yes
Carbon(COfo)
11%
Partical Size 40-60
urn
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
yes
Carbon(COfo)
65%
Partical Size 40-60
um
Silica Base
irregular shaped
Pore Size
52-68 A
Endcapped
No
Carbon(COfo)
7%
pI<,:
10.1 and 10.9
Organic anIalytes extraction
C1S has the broadest spectrum of
retention among bonded silica s o-bents, since it retains most organic
analytes from aqueoos matrices, when the corrp cunds of interest vaty
widely in structure
Desalting
When analyzing small to intermediate molecules,
Chrempure C1S can be used for desalting aquecus matrices pri ce to
icc exchange, as salts pass thrcugh the sa-bent unretained
Moderate Hydrophobicity
separating a wide range of compounds
and replace C1S when too strongly retention 00 C1S
Simultaneous Extraction:
fat- and water-solution vitamins from
human serum and herbicides, fungicides, pesticides frem waste
• Both
normal and reversed-phase
chrematography
• Less polar cempared to silica and less hydrophobic compared to
C1S and CS
• Usually used to extract acidic, neutral, and basic corrp ounds frem
aqueous soluti ons
• Similar selectivity to Chrempure NH2
• Strong affinity and high capacity fa- removing fatty acids,
crganic
acids, and some polar pigments and sugars when conducting
multi-residue pesticide analysis in foods
• Excellent sa-bent fa-
chelation
3
Chrompure NH
2
~NH2
Partical Size 40-60l-lill
Silica Base
irregular shaped
Pore Size
52-68A
Endcapped
No
Carbon(C%)
35%
pKa:
9.8
L..-__----'
• Amino propyl phase,
bcth hydrogen bending and anion exchange
• Weaker anion exchanger retention of very strong anicns such as
sulfcnic acids which may be retained irreversibly on SAX
• Separate peptides, drugs and metabolites from physiological fluids,
and extraction of mono- and polysaccharides, steroids, cholesterol
and triglycerides
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