R e s t e k
Considerations forBackbone-modified
Polysiloxane StationaryPhases:
•
By using a “low-bleed” column, you do not want
to give up selectivity.
–
Many “lowbleed” columns are dimethyl or
phenyl/methyl-type
•
ComputerAssistedStationaryPhaseDesign
(CASPD) utilized to optimize selectivity of
backbone-stabilized polymers for specific
applications
–
Anal. Chem.
74
(9), 2133-2138 2002.
–
LC*GC
18
(9), 928, 2000.
–
American Laboratory
,
31
(6), 20-26, 1999.