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153
HPLCCOLUMNS
Physical Characteristics
USPharmacopeiaCrossReference
L1
Octadecyl silane chemically bonded to porous silica or ceramicmicroparticles, 1.7 to 10µm in diameter, or amonolithic rod.
Ultra II C18 (p. 157), Ultra II Aqueous C18 (p. 159), PinnacleDB C18 (p. 166), PinnacleDBAqueous C18 (p. 171), Pinnacle II C18 (p. 173), Allure C18 (p. 178),
Allure Aqueous C18 (p. 179), Ultra C18 (p. 182), Ultra Aqueous C18 (p. 183), Viva C18 (p. 190)
L3
Porous silica particles, 5 to 10µm in diameter.
Ultra II Silica (p. 164), PinnacleDB Silica (p. 172), Pinnacle II Silica (p. 177), Allure Silica (p. 181), Ultra Silica (p. 188), Viva Silica (p. 193)
L7
Octylsilane chemically bonded to totally porous silica particles, 1.7 to 10µm in diameter.
Ultra II C8 (p. 158), PinnacleDB C8 (p. 167), Pinnacle II C8 (p. 174), Ultra C8 (p. 183), Viva C8 (p. 191)
L8
An essentiallymonomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 3 to 10µm in diameter.
Pinnacle II Amino (p. 176), Ultra Amino (p. 186)
L10
Nitrile groups chemically bonded to porous silica particles, 3 to 10µm in diameter.
PinnacleDB Cyano (p. 168), Pinnacle II Cyano (p. 175), Allure Basix (p. 178), Ultra Cyano (p. 185)
L11
Phenyl groups chemically bonded to porous silica particles, 1.7 to 10µm in diameter.
Ultra II Aromax (p. 161), Ultra II Biphenyl (p. 160), PinnacleDB Phenyl (p. 168),
PinnacleDBBiphenyl (p. 170), Pinnacle II Phenyl (p. 175), Pinnacle II Biphenyl (p. 176), Allure Biphenyl (p. 180), Ultra Phenyl (p. 186), Viva Biphenyl (p. 192)
L13
Trimethylsilane chemically bonded to porous silica particles, 3 to 10µm in diameter.
Ultra C1 (p. 185)
L26
Butyl silane chemically bonded to totally porous silica particles, 3 to 10µm in diameter.
Ultra C4 (p.184), Viva C4 (p.191)
L43
Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 5 to 10µm in diameter.
Ultra II PFP Propyl (p. 163), PinnacleDB PFP Propyl (p. 169), Allure PFP Propyl (p. 179), Ultra PFP (p. 187), Viva PFP Propyl (p. 192)
L68
Spherical, porous silica, 100µm or less in diameter, the surface of which has been covalentlymodifiedwith alkyl amide groups and not end capped.
Ultra II IBD (p. 162), PinnacleDB IBD (p. 171), Ultra IBD (p. 184)
Page
#
USP
Code
Similar Phases
Chromatographic Properties
High purity, highly retentive phase for aromatic and unsaturated compounds.
Unique
L11 180
High purity, highly retentive phase for normal phase separation of polar analytes. Very high surface area.
Maxsil Si
L3 181
A very retentive, high-purity phase that exhibits excellent peak shape for awide range of compounds.
Recommended as a general purpose reversed phase column.
Discovery C18, Symmetry C18, Hypersil Gold C18,
Luna C18, Zorbax C18, Kromasil C18,
LiChrospher RP-18, Inertsil ODS-2, Develosil C18
L1 182
Highly retentive and selective for reversed phase separations of polar analytes. Highly base deactivated.
Compatiblewith highly aqueous (up to 100%) mobile phases.
AQUA C18, Aquasil C18, Hypersil Gold AQ,
YMCODS-Aq
L1 183
One of a group of intrinsically base-deactivated (IBD) phases, with a polar groupwithin, or intrinsic to,
the alkyl bonded phase. Provides unique selectivity and high level of base deactivationwhile reducing or
eliminating the need formobile phase additives.
SymmetryShield, Discovery ABZ&ABZ+, Prism L68 184
Very retentive, high-purity, base-deactivated reversed phase packing that exhibits excellent peak shape
for awide range of compounds.
Luna C8, Symmetry C8, Hypersil Gold C8
L7 183
Exceptionally stable C4 packing, with high bonding coverage and silanol base-deactivation.
Exhibits shorter retention than C18 or C8 phases.
Supelcosil Butyl (C4), Delta-Pak C4
L26 184
Exceptionally stable C1 packing resists hydrolysis, even under acidicmobile phase conditions.
Least retentive reversed phase hydrocarbon packing.
Spherisorb C1
L13 185
High-purity cyano phasewith reduced silanol activity. Often a better choice than C18 for basic pharmaceuticals.
Cyano is themost stable bonded phase for normal phasemode.
Platinum CN, Develosil Cyano, Luna CN,
Hypersil Gold CN
L10 185
High-purity, highly retentive, base-deactivated phasewith alternate selectivity to hydrocarbon phases,
especially for aromatic analytes.
Platinum Phenyl, Supelcosil Phenyl,
Betasil Phenyl
L11 186
Recommended for normal phase analyses of mono- and disaccharides and other similar compounds.
Can also serve as aweak anion exchanger, with aqueous buffers.
PlatinumAmino, Develosil NH2
L8 186
A pentafluorophenyl phase. Unique selectivity by interactionwith functional groups of organohalogens
or other basic analytes.
Fluophase PFP, Fluosep-RP Phenyl,
Curosil PFP
L43 187
High purity, high surface area.
—
L3 188
Proprietary stationary phase can process up to twice asmany samples per hour, compared to a
conventional C18 phase.
Unique
— 188
High purity silica.
Unique
— 189
Silicamanufactured by Restek.
BioBasic 18, Symmetry 300 C18, Jupiter 300 C18,
Zorbax 300OSB C18, Synchropak C18, 208TP C18
L1 190
Silicamanufactured by Restek.
BioBasic 8, Zorbax 300OSB C8,
Synchropak C8, 208TP C8
L7 191
Silicamanufactured by Restek.
BioBasic 4, Symmetry 300 C4, Jupiter 300 C4,
Synchropak C4, 208TP C4
L26 191
Silicamanufactured by Restek.
Unique
L11 192
Silicamanufactured by Restek.
Unique
L43 192
Silicamanufactured by Restek.
—
L3 193
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Mar 2011
