○
○
○
○
○
○
○
○
○
○
○
○
○
○
○
○
23
Restek (U.S.):
110 Benner Circle, Bellefonte, PA 16823,
Phone:
(800) 356-1688,
Fax:
(814) 353-1309
Restek GmbH:
Sulzbacher Str. 15, D-65812 Bad Soden,
Telefon:
49-6196-65130,
Telefax:
49-6196-62301
Restek France:
1, rueMontespan, 91024 Evry Cedex,
Telefon:
33 01 60 78 32 10,
Telefax:
33 01 60 78 70 90
©Copyright 1997, Restek Corporation
Restek Trademarks:
Rtx, Rt-
β
DEX, and the Restek logo.
restek
CORPORATION
Lit. Cat. #59889
1. JohnMcMurray, OrganicChemistry, Brooks/Cole Pub., Monterey, CA, 1984.
2. C. Askari andA.Mosandl, Phytochem. Anal., Vol.2p.211 (1991).
3. Uzi Ravid, Eli Putievsky, and IrenaKatzir, “Chiral Analysis of Enantiomericallypure (R)-(-) Linalyl
Acetate in some Lamiaceae, Myrtle, andpetigrainEssential Oils,”
Flavour Fragrance J.
Vol.9,
Pp. 275-276 (1994).
4. Peter KreisandArminMosandl, “Chiral Compounds of Essential Oils. Part XIII. Simultaneous
ChiralityEvaluation of GeraniumOil Constituents.”
Flavour and Fragrance Journal,
Vol. 8. Pp.
161-168. (1993).
5. Peter Kreis andArminMosandl, “Chiral Compounds of Essential Oils. PartXII. Authenticity
Control of RoseOils, UsingEnantioselectiveMultidimensional GasChromatography.”
Flavour
and Fragrance Journal,
Vol. 7, Pp. 199-203 (1992).
6. W.A. Konig, C. Fricke, andY. Saritas, “Adulteration or Natural Variability?EnantiomericGC in
PurityControl of Essential Oils.”University of Hamburg, Institute of OrganicChemistry.
7. H.PNeukumandD.J. Meier, “Detection of Natural andReconstitutedBergamot Oil inEarl Grey
Teasby separation of theEnantiomers of Linalool andDihydrolinalool,”Mitt. Gebiete Lebensm.
Hyg., Vol. 84, Pp. 537-544 (1993).
8. AnnaArthoandKonradGrob, “Determination of
γ
-LactonesAdded to Foods as Flavors. HowFar
Must “Nature-Identical” Flavors be Identical withNature ?,”Mitte. Gebiete Lebensm. Hyg. Vol. 81,
Pp. 544-558 (1990).
9.
Physician’sDeskReference
, 46th ed., Pp. 1867-1868 (1992).
10.
Physicians’ DeskReference
, 46th ed., Pp. 2061-2062 (1992).
11.
Physicians’ DeskReference
, 46th ed., Pp. 514-515 (1992).
12. W. Haefely, E. Kyburz,M. Gerecke, andH.Mohler. “Recent Advances in themolecular
pharmacology of bezodiazepine receptorsand in the structure-activity relationships of their
agonists andantagonists.”
Adv. DrugRes.
Vol. 14, Pp. 165-322 (1985).
13. J.T. CodyandR. Schwartzhoff, “Interpretation of Methamphetamine andAmphetamine
Enantiomer Data”
J. Anal Toxicol.
Vol. 17, Pp. 321-326 (Oct. 1993).
PRODUCT LIST
For permission to reproduce any portion of this bulletin, please contact Restek’s publication/graphics department at (814)353-1300, ext. 2128.
Rt-
β
DEXsm
(30m, 0.25µm)
Rt-
β
DEXse
(30m, 0.25µm)
mm ID cat.# min. temp. max. temp.
mm ID cat.# min. temp. max. temp.
0.25 13105
40°C
230°C
0.25
13107
40°C
230°C
0.32 13104
40°C
230°C
0.32
13106
40°C
230°C
Rt-
β
DEXsa
(30m, 0.25µm)
Rt-
β
DEXsp
(30m, 0.25µm)
0.25 13109
40°C
230°C
0.25
13111
60°C
230°C
0.32 13108
40°C
230°C
0.32
13110
60°C
230°C
Rt-
β
DEXcst
(30m, 0.25µm)
Rt-
β
DEXm
(30m, 0.25µm)
0.25 13103
60°C
230°C
0.25
13100
40°C
230°C
0.32 13102
60°C
230°C
0.32
13101
40°C
230°C
Stereochemical proper-
ties of chiral drugs have
been found inmany in-
stances to be the control-
ling factor concerning
activity. One enantiomer
may provide a biological
function and the other
may be inactive ormay
exhibit another function-
ality, which could result
in side effects.
the federal guidelines for workplace
drug testing.
12
However,
l
-metham-
phetamine (deoxyephedrine) is found
in over-the-counter decongestants
and is not a controlled substance.
13
Enantiomeric separation of these
compounds, which is necessary for
accurate interpretation of drug tests,
is easily achieved on the Rt-
β
DEXcst
chiral capillary GC column (
Figure
27
).
